It is known that sperm production is leaded by genetic structures located on chromosomes and defects faced in these regions cause problems about sperm production, growth, and transformation. Genetic diseases affect sperm production for the worse in different ways. Therefore if tests turn no result to be able to define infertility problems, some genetic controls must be offered and must inform the reason of it. After finding some genetic distortions, the couples must again be informed, be mentioned about the risks etc.