New developments on genetic technology are providing genetic explorations on embryos, created as test tube baby. This method is called Preimplantation Genetic Diagnosis (PGD). PGD is realized by getting 1 or 2 cells from the embryos, developed by insemination of oocyte and sperm cells in the laboratory.

Specific methods are used on these cells and it is possible to diagnose structural chromosome distortions and gene diseases (Thalassaemia, Sickle Cell Anemia, Cystic Fibrosis etc). Therefore it is also possible to transfer healthy embryos to the mother and to have healthy babies.

The situations where PGT should be advised

• The diagnosis of the existence of structural or numerical chromosomes abnormalities on mother/father
• If both mother and father have the same single gene disorder.
• Either mother or father has single gene disorders
• On couples who are practiced assisted reproductive techniques (ART)

- Advanced maternal age (≥37)
- Couples suffering recurrent pregnancy loss
- Couples suffering male infertility
- Recurrent implantation failures